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Substrates

 

 

 

Substrates of abl, c-abl, BCR-abl 18 entries
Substrates Accession No Sites Reference
Caspase 9 P55211 Tyr153 Raina et al., 2005 J Biol Chem. 280:11147-11151
CD19 BCR coreceptor NP_001761 Tyr490=Tyr508 in NP_001761 Zipfel et al., 2000 J. Immunol. 165:6872-6879
Crk adaptor protein NP_058431 Tyr 221 Feller et al., 1994 EMBO J.13:2341-2351
DNA-Pk P78527 not mapped Kharbanda et al., 1997 Nature 386, 732-735
Dok1 Docking protein 1 Q99704 Tyr361 Woodring et al., 2004 J. Cell. Biol. 165:493-503
Fe65 adaptor protein AAL79526 Tyr547 Perkinton et al., 2004 JBC 279:22084-22091
HPK1 hematopoietic progenitor kinase 1 AAB97983 not mapped Ito et al., 2001 JBC 276::18130-18138
Hdm2 Mdm2 homologue human Q00987 Tyr394 Goldberg et al., 2002 EMBO J. 21:3715-3727
MEKK1, MAP3K1 Q13233 not mapped Kharbanda et al. 2000 MCB 20:4979-4989
PAK2, gamma PAK Q13177 not mapped Roig et al., 2000 PNAS USA 97:14346-14351
Phospholipid scramblase 1 NP_066928 Tyr69 and/or Tyr74 Sun et al., 2001 JBC 276:28984-28990
PKD protein kinase D Q15139 Tyr463 Storz et al., 2003 JBC 278:17969-17976
p73  NP_005418   Agami et al., 1999 Nature 399:809-813
Rad9 NP_004575 Tyr28 Yoshida et al., 2002 MCB 22:3292-300
Rad 51  several isoforms  Tyr54  Yuan et al., 1998 JBC 273:3799-3802
RAFT1, FRAP1, FK506 binding protein 12-rapamycin associated protein 1 NP_004949 not mapped Kumar et al., 2000 JBC 275:10779-10787
RNA-Pol II  NP_000928 C-terminus YSPTSPS repeat

Baskara et al., 1993 PNAS USA. 90:10896-7

TERT telomerase reverse transcriptase NP_003210 not mapped Kharbanda et al., 2000 Curr. Biol. 10:568-575

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