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Substrates
|
| Substrates
of CDK2 with cyclin A or cyclin E |
| Substrates |
Accession
No |
Sites |
Reference |
| Axin |
NP_003493 |
Thr481,
Ser486, Ser493 |
Kim et
al., 2004 BBRC 478-83 |
| B-Myb |
P10244 |
T447,
T490, T497 ± a few aa |
Saville
& Watson 1998 Oncogene 17:2679-2689 |
| Brca1 |
NP_009226 |
Ser1497 |
Ruggner
et al., 1999 MCB 19:4843-4853 |
| CP110 |
NP 055526 |
|
Chen et
al.,2002, Dev.Cell 3:339-350 |
| CDK7 |
NP_1790 |
Ser164,
Thr170 |
Garret
et al., 2001 MCB 21:88-89 |
| pRb Retinoblastoma
protein |
NP_000312 |
many |
Akiyama
et al., 1992 PNAS 1992 89:7900:7004 |
| E2F |
AAH58902 |
|
Kitagiwa
et al., 1995 Oncogene 10:229-236 |
| HsCdc6 |
NP_001245 |
Ser54,
Ser74, Ser106 |
Jiang
et al., 1999 PNAS USA 96:6193-6198 |
| p27 Kip |
P46527 |
Thr187 |
Sheaff
et al., 1997 Genes Dev. 11:1464-1478
Xu et al., 1999 Biochemistry 38:8713-8722 |
| PP1 alpha |
P08129 |
Thr320 |
Liu et
al., 1999 JBC 274:29470-29475 |
| p53 |
NP_000537 |
Ser315 |
Price
et al., 1995 Oncogene 11:73-80 |
| p220 NPAT |
NP_002510 |
S775,
S779, S1100, T1270, T1350 |
Ma et
al., 2000 Genes Dev. 14:2298-2318 |
| Ig protein
VZV |
AAK01046 |
Ser344 |
Ye et
al., 1999 J. Virol. 73:1320-1330 |
| MARCKS |
A33873 |
Ser27,
Thr150 |
Manenti
et al., 1999 Biochem. J. 340:775-782 |
| Myo-D |
CAA40000 |
Ser200 |
Tintignac
et al., 2000 Exp. Cell Res. 259:300-307 |
| Nucleophosmin
B23 |
NP_00511 |
Ser70 |
Okuda
et al., 2000 Cell 103:127-140 |
| Ribonucleotide
reductase M2 |
NP_001025 |
Ser20 |
Chan
et al., 1993 Biochemistry 32:12835-12840
Chan et al., 1999 BBA 1448:363-371 |
| RNA Pol
II CTD |
P24928 |
Ser2 of
CTD repeat |
Nekhai
et al., 2002 Biochem J. 264:649-657 |
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