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Substrates

 

 

 

Substrates of c-Raf = Raf-1
Substrates Acc. No. Sites Reference
MEK-1 = MAPKK1 = MAP2K1 = MKK1 Q02750 Ser217, Ser221 Alessi et al., 1994 EMBO J. 13:1610-1619
MEK-2 = MAPKK2 = MAP2K2 = MKK2 P36507 Ser222, Ser226 Equivalent to MEK1
p53 NP_000537   Jamal & Ziff 1995 Oncogene 10:2095-2101
RIP-2 = RIPK-2 O43353 not mapped Navas et al., 1999 JBC 274(47):33684-33690
Tvl-1 = RFXANK (mouse sequence) Q9Z205 not mapped Lin et al., 1999 JBC 274(21):14706-15

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